Prior O, Macarro C, Navarro V, Monreal C, Ligero M, Garcia-Ruiz A, Serna G, Simonetti S, Braña I, Vieito M, Escobar M, Capdevila J, Byrne AT, Dienstmann R, Toledo R, Nuciforo P, Garralda E, Grussu F, Bernatowicz K, Perez-Lopez R. Identification of Precise 3D CT Radiomics for Habitat Computation by Machine Learning in Cancer. Radiol Artif Intell. 2024 Mar;6(2):e230118. doi: 10.1148/ryai.230118.PMID: 38294307

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Connor K, Conroy E, White K, Shiels LP, Keek S, Ibrahim A, Gallagher WM, Sweeney KJ, Clerkin J, O'Brien D, Cryan JB, O'Halloran PJ, Heffernan J, Brett F, Lambin P, Woodruff HC, Byrne AT. A clinically relevant computed tomography (CT) radiomics strategy for intracranial rodent brain tumour monitoring.  Sci Rep. 2024 Feb 1;14(1):2720. doi: 10.1038/s41598-024-52960-1. PMID: 38302657

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Fabro F, Kers TV, Feller KJ, Beerens C, Ntafoulis I, Idbaih A, Verreault M, Connor K, Biswas A, Salvucci M, Prehn J, Byrne A, O'Farrell A, Lambrechts D, Dilcan G, Lodi F, Arijs I, Kremer A, Yen RTC, Chien M-P, Lamfers MLM, Leenstra S. Genomic exploration of distinct molecular phenotypes steering temozolomide resistance development in patient-derived glioblastoma cells. Int J Mol Sci. 2023 Oct 27;24(21):15678.  doi: 10.3390/ijms242115678.

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Ntafoulis I, Kleijn A, Ju J, Jimenez-Cowell K, Fabro F, Klein M, Chi Yen RT, Balvers RK, Li Y, Stubbs AP, Kers TV, Kros JM, Lawler SE, Beerepoot LV, Kremer A, Idbaih A, Verreault M, Byrne AT, O'Farrell AC, Connor K, Biswas A, Salvucci M, Prehn JHM, Lambrechts D, Dilcan G, Lodi F, Arijs I, van den Bent MJ, Dirven CMF, Leenstra S; GLIOTRAIN consortium; Lamfers MLM. Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers. Br J Cancer. 2023 Oct;129(8):1327-1338.  doi: 10.1038/s41416-023-02402-y

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Biswas A, Salvucci M, Connor K, Düssmann H, Carberry S, Fichtner M, King E, Murphy B, O'Farrell AC, Cryan J, Beausang A, Heffernan J, Cremona M, Hennessy BT, Clerkin J, Sweeney KJ, MacNally S, Brett F, O'Halloran P, Bacon O, Furney S, Verreault M, Quissac E, Bielle F, Ahmed MH, Idbaih A, Leenstra S, Ntafoulis I, Fabro F, Lamfers M, Golebiewska A, Hertel F, Niclou SP, Yen RTC, Kremer A, Dilcan G, Lodi F, Arijs I, Lambrechts D, Purushothama MK, Kel A, Byrne AT, Prehn JHM. Comparative analysis of deeply phenotyped GBM cohorts of 'short-term' and 'long-term' survivors. J Neurooncol. 2023 Jun;163(2):327-338.  doi: 10.1007/s11060-023-04341-3

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Caulfield C, Wu D, Miller IS, Byrne AT, Mac Aonghusa P, Zhuk S, Cinelli L, Bannone E, Marescaux J, Gioux S, Diana M, March TL, Vahrmeijer AL, Cahill R, O'Shea DF. BF2-Azadipyrromethene Fluorophores for Intraoperative Vital Structure Identification. Molecules. 2023 Feb 25;28(5):2167. doi: 10.3390/molecules28052167.

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White K, Connor K, Meylan M, Bougoüin A, Salvucci M, Bielle F, O’Farrell AC, Sweeney K, Weng L, Bergers G, Dicker P, Ashley DM, Lipp ES, Low JT, Zhao J, Wen P, Prins R, Verreault M, Idbaih A, Biswas A, Prehn JHM, Lambrechts D, Arijs I, Lodi F, Dilcan G, Lamfers M, Leenstra S, Fabro F, Ntafoulis I, Kros JM, J.Cryan, Brett F, Quissac E, Beausang A, MacNally S, O’Halloran P, Clerkin J, Bacon O, Kremer A, Tching Chi Yen R, Varn FS, Verhaak RGW, Sautès-Fridman C, Fridman WH, Byrne AT.  Identification, validation and biological characterization of novel Glioblastoma Tumour Microenvironment subtypes: Implications for precision immunotherapy. Ann Oncol. 2023 Mar;34(3):300-314. doi: 10.1016/j.annonc.2022.11.008

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Varn FS, Johnson KC, JMartinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D’Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell, 2022, https://doi.org/10.1016/j.cell.2022.04.038

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Netufo O, Connor K, Shiels LP, Sweeney KJ, Wu D, O’Shea DF, Byrne AT, Miller IS. Refining Glioblastoma Surgery through the Use of Intra-Operative Fluorescence Imaging Agents. Pharmaceuticals. 2022, 15(5), 550: https://doi.org/10.3390/ph15050550

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Miller IS, Khan S, Shiels LP, Das S, O' Farrell AC, Connor K, Lafferty A, Moran B, Isella C, Loadman P, Conroy E, Cohrs S, Schibli R, Kerbel RS, Gallagher WM, Marangoni E, Bennett K, O' Connor DP, Dwyer RM, Byrne AT. Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects.Cancer Med. 2022 Apr 17. doi: 10.1002/cam4.4756.

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Lafferty A, O'Farrell AC, Migliardi G, Khemka N, Lindner AU, Sassi F, Zanella ER, Salvucci M, Vanderheyden E, Modave E, Boeckx B, Halang L, Betge J, Ebert MPA, Dicker P, Argilés G, Tabernero J, Dienstmann R, Medico E, Lambrechts D, Bertotti A, Isella C, Trusolino L, Prehn JHM, Byrne AT. Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer. Clin Cancer Res. 2021 Aug 23. doi: 10.1158/1078-0432.CCR-21-0818.

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Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Serra V, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA 2nd, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE, Lewis MT, Fang B, Roth JA, Meric-Bernstam F, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH; PDXNET Consortium; EurOPDX Consortium. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet. Jan;53(1):86-99. doi: 10.1038/s41588-020-00750-6.

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Connor K, Murray DW, Jarzabek MA, Tran NL, White K, Dicker P, Sweeney KJ, O'Halloran PJ, MacCarthy B, Shiels LP, Lodi F, Lambrechts D, Sarkaria JN, Schiffelers RM, Symons M, Byrne AT. Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies. Cancers (Basel). 2020 Nov 26;12(12):E3531. doi: 10.3390/cancers12123531.

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O'Farrell AC, Jarzabek MA, Lindner AU, Carberry S, Conroy E, Miller IS, Connor K, Shiels L, Zanella ER, Lucantoni F, Lafferty A, White K, Meyer Villamandos MM, Dicker P, Gallagher WM, Keek SA, Sanduleanu S, Lambin P, Woodruff HC, Bertotti A, Trusolino L, Byrne AT, Prehn JHM. Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models. Cancers (Basel). 2020 Oct 14;12(10):E2978. doi: 10.3390/cancers12102978.

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White K, Connor K, Clerkin J, Murphy BM, Salvucci M, O'Farrell AC, Rehm M, O'Brien D, Prehn JHM, Niclou SP, Lamfers MLM, Verreault M, Idbaih A, Verhaak R, Golebiewska A, Byrne AT. New hints towards a precision medicine strategy for IDH wild-type glioblastoma. Ann Oncol. 2020 Sep 9:S0923-7534(20)42428-7. doi: 10.1016/j.annonc.2020.08.2336.

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Barat A, Smeets D, Moran B, Zhang W, Cao S, Das S, Klinger R, Betge J, Murphy V, Bacon O, Kay E.W, Van Grieken N.C.T, Verheul H.M.W, Gaiser T, Schulte N, Ebert M.P, Fender B, Hennessy B.T, McNamara D.A, O'Connor D, Gallagher W.M, Cremolini C, Loupakis F, Parikh A, Mancao C, Ylstra B, Lambrechts D, Lenz H.J, Byrne A.T, Prehn J.H.M. Combination of Variations in Inflammation- And Endoplasmic Reticulum-Associated Genes as Putative Biomarker for Bevacizumab Response in KRAS Wild-Type Colorectal Cancer. Sci Rep. 2020 Jun 17;10(1):9778. doi: 10.1038/s41598-020-65869-2.

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Dienstmann R, Connor K, Byrne AT. Precision Therapy in RAS Mutant Colorectal Cancer.

Gastroenterology. 2020 Mar;158(4):806-811. doi: 10.1053/j.gastro.2019.12.051. Epub 2020 Jan 21. 

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 Fridman WH, Miller I, Sautès-Fridman C, Byrne AT. Therapeutic Targeting of the Colorectal Tumor Stroma.  Gastroenterology. 2020 Jan;158(2):303-321. doi: 10.1053/j.gastro.2019.09.045. Epub 2019 Oct 14. Review.

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Noonan JJ, Jarzabek M, Lincoln FA, Cavanagh BL, Pariag AR, Juric V, Young LS, Ligon KL, Jahns H, Zheleva D, Prehn JHM, Rehm M, Byrne AT, Murphy BM. Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma.  Cancers (Basel). 2019 Dec 12;11(12). pii: E2005. doi: 10.3390/cancers11122005.

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Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, Betge J, Härtel N, Kather JN, Weis CA, Gaiser T, Marx A, Weiss C, Hofheinz R, Miller IS, Loupakis F, Lenz HJ, Byrne AT, Ebert MP. Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A. EBioMedicine. 2019 Jul;45:139-154. doi: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9.

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Miller IS, Shiels LP, Conroy E, Connor K, Dicker P, Gallagher WM, Donovan NO, Kerbel RS, Crown J, Byrne AT. Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents. Sci Rep. 2019 Jun 24;9(1):9204. doi: 10.1038/s41598-019-45444-0.

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Gullo G, J. Eustace A, Canonici A, M. Collins D, Kennedy MJ, Grogan L, Breathhnach O, McCaffrey J, Keane M, Martin MJ, Gupta R, Leonard G, O’Connor M, Calvert PM, Donnellan P, Walshe J, McDermott E, Scott K, Hernando A, Parker I, W. Murray D, C. O’Farrell A, Maratha A, Dicker P, Rafferty M, Murphy V, O’Donovan N, M. Gallagher W, Ky B, Tryfonopoulos D, Moulton B, T. Byrne A, Crown J.  Pilot study of bevacizumab in combination with docetaxel and cyclophosphamide as adjuvant treatment for patients with early stage HER-2 negative breast cancer, including analysis of candidate circulating markers of cardiac toxicity: ICORG 08–10 trial. Therapeutic Advances in Medical Oncology. 11. Published 1 Jul 2019

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Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, et al. When Ron met Tam in mesothelioma: All druggable for one, and one drug for all?. Frontiers in Endocrinology. 10(FEB) 01 Jan 2019 (Journal article)

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Lou B, Connor K, Sweeney K, Miller IS, O’Farrell A, Ruiz-Hernandez E, Murray DM, Duffy GP, Wolfe A, Mastrobattista E, et al. RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells. Drug Delivery and Translational Research 9(3):679-693 15 Jun 2019 (Journal article)

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O'Farrell AC, Miller IS, Evans R, Alamanou M, Cary M, Mallya Udupi G, Lafferty A, Monsefi N, Cremona M, Prehn JHM, et al. Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate. Proteomics - Clinical Applications 01 Jan 2019 (Journal article)

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Sturrock M, Miller IS, Kang G, Arba’ie NH, O’Farrell AC, Barat A, Marston G, Coletta PL, Byrne AT, Prehn JH. Erratum to: Anti-angiogenic drug scheduling optimisation with application to colorectal cancer (Scientific Reports, (2018), 8, 1, (11182), 10.1038/s41598-018-29318-5) Scientific Reports 8(1) 01 Dec 2018 (Journal article)

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Sturrock M, Miller IS, Kang G, Hannis Arba’ie N, O’Farrell AC, Barat A, Marston G, Coletta PL, Byrne AT, Prehn JH. Anti-angiogenic drug scheduling optimisation with application to colorectal cancer. Scientific Reports 8(1) 01 Dec 2018 (Journal article)

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Smeets D, Miller IS, O’Connor DP, Das S, Moran B, Boeckx B, Gaiser T, Betge J, Barat A, Klinger R, et al. Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy. Nature Communications 9(1) 01 Dec 2018 (Journal article)

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Van Dijk E, Biesma HD, Cordes M, Smeets D, Neerincx M, Das S, Eijk PP, Murphy V, Barat A, Bacon O, et al. Loss of chromosome 18q11.2-q12.1 is predictive for survival in patients with metastatic colorectal cancer treated with bevacizumab. Journal of Clinical Oncology 36(20):2052-2060 10 Jul 2018 (Journal article)

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Jarzabek MA, Proctor WR, Vogt J, Desai R, Dicker P, Cain G, Raja R, Brodbeck J, Stevens D, van der Stok EP, et al. Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer. PLoS ONE 13(6) 01 Jun 2018 (Journal article)

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Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, et al. PDX-MI: Minimal information for patient-derived tumor xenograft models. Cancer Research 77(21):e62-e66 01 Nov 2017 (Journal article)

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Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, et al. Interrogating open issues in cancer medicine with patient-derived xenografts. Nature reviews. Cancer 17(10):632 15 Sep 2017 (Journal article)

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Moran B, Das S, Smeets D, Peutman G, Klinger R, Fender B, Connor K, Ebert M, Gaiser T, Prehn JHM, et al. Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach. Oncotarget 8(29):48126-48137 01 Jan 2017 (Journal article)

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Zuurbier L, Rahman A, Cordes M, Scheick J, Wong TJ, Rustenburg F, Joseph JC, Dynoodt P, Casey R, Drillenburg P, et al. Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer. Oncotarget 8(26):42949-42961 01 Jan 2017 (Journal article)

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Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, et al. Interrogating open issues in cancer precision medicine with patient-derived xenografts. Nature Reviews Cancer 17(4):254-268 01 Apr 2017 (Journal article)

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Kang G, Márquez C, Barat A, Byrne AT, Prehn JHM, Sorribes J, César E. Colorectal tumour simulation using agent based modelling and high performance computing. Future Generation Computer Systems 67:397-408 01 Feb 2017 (Journal article)

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O'Farrell AC, Evans R, Silvola JMU, Miller IS, Conroy E, Hector S, Cary M, Murray DW, Jarzabek MA, Maratha A, et al. A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate. PLoS ONE 12(1) 01 Jan 2017 (Journal article)

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Connor K, Jarzabek MA, White K, Jacobs AH, Byrne AT. Imaging Targeted Therapy Response and Resistance in Glioblastoma In Resistance to Targeted Therapies Against Adult Brain Cancers. Editors: Bonavida, Benjamin. 175-198. Springer 16 Dec 2016 (Chapter)

Joerger M, Finn SP, Cuffe S, Byrne AT, Gray SG. The IL-17-Th1/Th17 pathway: an attractive target for lung cancer therapy?. Expert Opinion on Therapeutic Targets 20(11):1339-1356 01 Nov 2016 (Journal article)

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Rudolph M, Anzeneder T, Schulz A, Beckmann G, Byrne AT, Jeffers M, Pena C, Politz O, Köchert K, Vonk R, et al. AKT1 ^E17K mutation profiling in breast cancer: Prevalence, concurrent oncogenic alterations, and blood-based detection. BMC Cancer 16(1) 01 Jan 2016 (Journal article)

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Besenhard MO, Jarzabek M, O'Farrell AC, Callanan JJ, Prehn JH, Byrne AT, Huber HJ. Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements. Journal of Theoretical Biology 402:129-143 07 Aug 2016 (Journal article)

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O’Halloran PJ, Viel T, Murray DW, Wachsmuth L, Schwegmann K, Wagner S, Kopka K, Jarzabek MA, Dicker P, Hermann S, et al. Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers. European Journal of Nuclear Medicine and Molecular Imaging 43(9):1673-1683 01 Aug 2016 (Journal article)

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Boland K, Flanagan L, McCawley N, Pabari R, Kay EW, McNamara DA, Murray F, Byrne AT, Ramtoola Z, Concannon CG, et al. Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer. European Journal of Pharmacology 780:53-64 05 Jun 2016 (Journal article)

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Zakaria Z, Tivnan A, Flanagan L, Murray DW, Salvucci M, Stringer BW, Day BW, Boyd AW, Kögel D, Rehm M, et al. Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant. British Journal of Cancer 114(2):188-198 19 Jan 2016 (Journal article)

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Szwej E, Devocelle M, Kenny S, Guzik M, O'Connor S, Nikodinovic-Runic J, Radivojevic J, Maslak V, Byrne AT, Gallagher WM, et al. The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides. Journal of Biotechnology 204:7-12 01 Jun 2015 (Journal article)

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Temple D, Denis R, Walsh MC, Dicker P, Byrne AT. Comparison of anthropometric-based equations for estimation of body fat percentage in a normal-weight and overweight female cohort: Validation via air-displacement plethysmography. Public Health Nutrition 18(3):446-452 10 Mar 2015 (Journal article)

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Barat A, Ruskin HJ, Byrne AT, Prehn JHM. Integrating Colon Cancer Microarray Data: Associating Locus-Specific Methylation Groups to Gene Expression-Based Classifications. Microarrays (Basel, Switzerland) 4(4):630-646 Jan 2015 (Journal article)

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Byrne AT, Arnett R, Farrell T, Sreenan S. Comparison of performance in a four year graduate entry medical programme and a traditional five/six year programme. BMC Medical Education 14(1) 01 Jan 2014 (Journal article)

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Jarzabek MA, Amberger-Murphy V, Callanan JJ, Gao C, Zagozdzon AM, Shiels L, Wang J, Ligon KL, Rich BE, Dicker P, et al. Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models. British Journal of Cancer 111(12):2275-2286 09 Dec 2014 (Journal article)

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Hidalgo M, Amant F, Biankin AV, Budinská E, Byrne AT, Caldas C, Clarke RB, de Jong S, Jonkers J, Mælandsmo GM, et al. Patient-derived Xenograft models: An emerging platform for translational cancer research. Cancer Discovery 4(9):998-1013 01 Jan 2014 (Journal article)

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Sweeney KJ, Jarzabek MA, Dicker P, O'Brien DF, Callanan JJ, Byrne AT, Prehn JHM. Validation of an imageable surgical resection animal model of Glioblastoma (GBM). Journal of Neuroscience Methods 233:99-104 15 Aug 2014 (Journal article)

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Rani S, Corcoran C, Shiels L, Germano S, Breslin S, Madden S, McDermott MS, Browne BC, O'Donovan N, Crown J, et al. Neuromedin U: A candidate biomarker and therapeutic target to predict and overcome resistance to HER-tyrosine kinase inhibitors. Cancer Research 74(14):3821-3833 15 Jul 2014 (Journal article)

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Murray DW, Didier S, Chan A, Paulino V, Van Aelst L, Ruggieri R, Tran NL, Byrne AT, Symons M. Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation. British Journal of Cancer 110(5):1307-1315 04 Mar 2014 (Journal article)

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van Cutsem E, Prager G, Sargent D, Byrne AT, Huber HJ, Middleton G, Khan K, De Mattos-Arruda L, Seufferlein T. Biomarker-driven studies in metastatic colorectal cancer (mCRC): Challenges and opportunities. Journal of OncoPathology 2(4):37-45 01 Jan 2014 (Journal article)

Jarzabek MA, Sweeney KJ, Evans RL, Jacobs AH, Stupp R, O'Brien D, Berger MS, Prehn JHM, Byrne AT. Molecular imaging in the development of a novel treatment paradigm for glioblastoma (GBM): An integrated multidisciplinary commentary. Drug Discovery Today 18(21-22):1052-1066 01 Nov 2013 (Journal article)

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Jarzabek MA, Huszthy PC, Skaftnesmo KO, McCormack E, Dicker P, Prehn JHM, Bjerkvig R, Byrne AT. In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme. Molecular Imaging. 12(3) 01 May 2013 (Journal article)

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O'Connor S, Szwej E, Nikodinovic-Runic J, O'Connor A, Byrne AT, Devocelle M, O'Donovan N, Gallagher WM, Babu R, Kenny ST, et al. The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate. Biomaterials. 34(11):2710-2718 01 Apr 2013 (Journal article)

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O'Connor AE, Mc Gee MM, Likar Y, Ponomarev V, Callanan JJ, O'Shea DF, Byrne AT, Gallagher WM. Mechanism of cell death mediated by a BF <inf>2</inf> -chelated tetraaryl-azadipyrromethene photodynamic therapeutic: Dissection of the apoptotic pathway in vitro and in vivo. International Journal of Cancer. 130(3):705-715 01 Feb 2012 (Journal article)

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Vader P, Van Der Meel R, Symons MH, Fens MHAM, Pieters E, Wilschut KJ, Storm G, Jarzabek M, Gallagher WM, Schiffelers RM, et al. Examining the role of Rac1 in tumor angiogenesis and growth: A clinically relevant RNAi-mediated approach. Angiogenesis. 14(4):457-466 01 Dec 2011 (Journal article)

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O'Donovan N, Byrne AT, O'Connor AE, McGee S, Gallagher WM, Crown J. Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells. Investigational New Drugs. 29(5):752-759 01 Oct 2011 (Journal article)

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Van Der Meel R, Symons MH, Kudernatsch R, Kok RJ, Schiffelers RM, Storm G, Gallagher WM, Byrne AT. The VEGF/Rho GTPase signalling pathway: A promising target for anti-angiogenic/anti-invasion therapy. Drug Discovery Today. 16(5-6):219-228 01 Mar 2011 (Journal article)

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Fitzpatrick SF, Tambuwala MM, Bruning U, Schaible B, Scholz CC, Byrne A, O'Connor A, Gallagher WM, Lenihan CR, Garvey JF, et al. An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. Journal of Immunology. 186(2):1091-1096 15 Jan 2011 (Journal article)

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Fens MHAM, Storm G, Pelgrim RCM, Ultee A, Byrne AT, Gaillard CA, van Solinge WW, Schiffelers RM. Erythrophagocytosis by angiogenic endothelial cells is enhanced by loss of erythrocyte deformability. Experimental Hematology. 38(4):282-291 01 Apr 2010 (Journal article)

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O'Neill K, Lyons SK, Gallagher WM, Curran KM, Byrne AT. Bioluminescent imaging: A critical tool in pre-clinical oncology research. Journal of Pathology. 220(3):317-327 01 Feb 2010 (Journal article)

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van der Meel R, Gallagher WM, Oliveira S, O'Connor AE, Schiffelers RM, Byrne AT. Recent advances in molecular imaging biomarkers in cancer: application of bench to bedside technologies. Drug Discovery Today. 15(3-4):102-114 01 Feb 2010 (Journal article)

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Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, et al. Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence. Experimental Cell Research. 316(2):258-271 15 Jan 2010 (Journal article)

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Byrne AT, O'Connor AE, Hall M, Murtagh J, O'Neill K, Curran KM, Mongrain K, Rousseau JA, Lecomte R, McGee S, et al. Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: A multi-modality molecular imaging approach to therapeutic assessment. British Journal of Cancer. 101(9):1565-1573 03 Nov 2009 (Journal article)

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Nacht M, St. Martin TB, Byrne A, Klinger KW, Teicher BA, Madden SL, Jiang Y. Netrin-4 regulates angiogenic responses and tumor cell growth. Experimental Cell Research. 315(5):784-794 10 Mar 2009 (Journal article)

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O'Connor AE, Gallagher WM, Byrne AT. Porphyrin and nonporphyrin photosensitizers in oncology: Preclinical and clinical advances in photodynamic therapy. Photochemistry and Photobiology. 85(5):1053-1074 01 Sep 2009 (Journal article)

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McDonnell SO, Hall MJ, Allen LT, Byrne A, Gallagher WM, O'Shea DF. Supramolecular photonic therapeutic agents. Journal of the American Chemical Society. 127(47):16360-16361 30 Nov 2005 (Journal article)

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Byrne AT, Ross L, Holash J, Nakanishi M, Hu L, Hofmann JI, Yancopoulos GD, Jaffe RB. Vascular Endothelial Growth Factor-Trap Decreases Tumor Burden, Inhibits Ascites, and Causes Dramatic Vascular Remodeling in an Ovarian Cancer Model. Clinical Cancer Research. 9(15):5721-5728 15 Nov 2003 (Journal article)

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Geva E, Ginzinger DG, Zaloudek CJ, Moore DH, Byrne A, Jaffe RB. Human placental vascular development: Vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2. Journal of Clinical Endocrinology and Metabolism. 87(9):4213-4224 01 Sep 2002 (Journal article)

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2002

Byrne AT, Southgate J, Brison DR, Leese HJ. Regulation of apoptosis in the bovine blastocyst by insulin and the insulin-like growth factor (IGF) superfamily. Molecular Reproduction and Development. 62(4):489-495 18 Jul 2002 (Journal article)

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Byrne AT, Southgate J, Brison DR, Leese HJ. Effects of insulin-like growth factors I and II on tumour-necrosis-factor-α-induced apoptosis in early murine embryos. Reproduction, Fertility and Development. 14(1-2):79-83 23 May 2002 (Journal article)

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Byrne AT, Southgate J, Brison DR, Leese HJ. Analysis of apoptosis in the preimplantation bovine embryo using TUNEL. Journal of Reproduction and Fertility. 117(1):97-105 01 Jan 1999 (Journal article)

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